95399-71-6
95399-71-6
Chemical Structure
Fosfenopril
Synonym(s): Fosinoprilat; Fosinoprilic acid; SQ 27519
- CAS No.: 95399-71-6
- Formula:C23H34NO5P
- Molecular Weight:435.49
IUPAC Name: (2S,4S)-4-cyclohexyl-1-(2-(hydroxy(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylic acid
InChIKey: WOIWWYDXDVSWAZ-RTWAWAEBSA-N
SMILES: O=P(CCCCC1=CC=CC=C1)(O)CC(N2C[C@H](C3CCCCC3)C[C@H]2C(O)=O)=O
Biological Activity: Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fosfenopril | 99.85% | Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. | ||||||||||||||||||||
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Fosfenopril (Standard) | ≥98% | Fosfenopril (Standard) is the analytical standard of Fosfenopril. This product is intended for research and analytical applications. Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. | ||||||||||||||||||||
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Fosfenopril-d7 | Fosfenopril-d7 is deuterium labeled Fosfenopril. | |||||||||||||||||||||
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References
- [1]. Yang S, et al. Fosinoprilat alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. Cell Immunol. 2013 Jul-Aug;284(1-2):182-6. [Content Brief]
- [2]. DeForrest JM, et al. Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology. J Cardiovasc Pharmacol. 1989 Nov;14(5):730-6. [Content Brief]
