95853-92-2
95853-92-2
Chemical Structure
CGS 15435
- CAS No.: 95853-92-2
- Formula:C20H21ClN2O2
- Molecular Weight:356.85
IUPAC Name: 6-(5-chloro-1-methyl-2-(pyridin-3-yl)-1H-indol-3-yl)hexanoic acid
InChIKey: BYQANTGKEVLUKZ-UHFFFAOYSA-N
SMILES: O=C(O)CCCCCC1=C(C2=CC=CN=C2)N(C)C3=C1C=C(Cl)C=C3
Biological Activity: CGS 15435, a potent thromboxane (TxA2) synthetase inhibitor with an IC50 of 1 nM, has a selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI2 synthetase and lipoxygenase enzymes.
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CGS 15435 | CGS 15435, a potent thromboxane (TxA2) synthetase inhibitor with an IC50 of 1 nM, has a selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI2 synthetase and lipoxygenase enzymes. | |||||||||||||||||||||
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