961-07-9
961-07-9
Chemical Structure
2'-Deoxyguanosine
Synonym(s): Deoxyguanosine; Guanine deoxyriboside
- CAS No.: 961-07-9
- Formula:C10H13N5O4
- Molecular Weight:267.25
IUPAC Name: 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: YKBGVTZYEHREMT-KVQBGUIXSA-N
SMILES: OC[C@@H](O[C@H](C1)N2C3=C(N=C2)C(NC(N)=N3)=O)[C@H]1O
Biological Activity: 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2'-Deoxyguanosine | 99.90% | 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells. | ||||||||||||||||||||
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2'-Deoxyguanosine (Standard) | 99.21% | 2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells.
In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively. |
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2'-Deoxyguanosine-13C10 | 99.8% | 2'-Deoxyguanosine-13C10 (Deoxyguanosine-13C10; Guanine deoxyriboside-13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine. | ||||||||||||||||||||
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2'-Deoxyguanosine-d13 | 99.9% | 2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine. | ||||||||||||||||||||
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2'-Deoxyguanosine-15N5 | 99.80% | 2'-Deoxyguanosine-15N5 (Deoxyguanosine-15N5; Guanine deoxyriboside-15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine. | ||||||||||||||||||||
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2'-Deoxyguanosine-13C10,15N5 | 2'-Deoxyguanosine-13C10,15N5 (Deoxyguanosine-13C10,15N5; Guanine deoxyriboside-13C10,15N5) is a 13C- and 15N-labeled 2'-Deoxyguanosine (HY-17563). | |||||||||||||||||||||
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2'-Deoxyguanosine-13C,15N2 | 2'-Deoxyguanosine-13C,15N2 (Deoxyguanosine-13C,15N2; Guanine deoxyriboside-13C,15N2) is the 13C- and 15N-labeled labeled 2'-Deoxyguanosine (HY-17563). 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells. | |||||||||||||||||||||
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References
- [1]. Ross DD, et al. Effects of deoxynucleosides on cultured human leukemia cell growth and deoxynucleotide pools. Cancer Res. 1981 Nov;41(11 Pt 1):4493-8. [Content Brief]
- [2]. Kizaki H, et al. Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes. J Immunol. 1988 Sep 1;141(5):1652-7. [Content Brief]
- [3]. Brulfert A, et al. Deoxyguanosine, a potent cytokinesis inhibitor in plant cells. Experientia. 1974 Sep 15;30(9):1010-1. [Content Brief]
