98206-09-8
98206-09-8
Chemical Structure
Eltoprazine hydrochloride
Synonym(s): DU 28853 hydrochloride
- CAS No.: 98206-09-8
- Formula:C12H17ClN2O2
- Molecular Weight:256.73
IUPAC Name: 1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine hydrochloride
InChIKey: JFSOSUNPIXJCIX-UHFFFAOYSA-N
SMILES: [H]Cl.N1(C2=C3OCCOC3=CC=C2)CCNCC1
Biological Activity: Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects[1][2].
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Eltoprazine hydrochloride | 99.25% | Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects. | ||||||||||||||||||||
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Eltoprazine hydrochloride (Standard) | ≥98% | Eltoprazine (hydrochloride) (Standard) is the analytical standard of Eltoprazine (hydrochloride). This product is intended for research and analytical applications. Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects. | ||||||||||||||||||||
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References
- [1]. Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. [Content Brief]
- [2]. Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31. [Content Brief]
