98946-18-0
98946-18-0
Chemical Structure
tert-Butyl 2,2,2-trichloroacetimidate
- CAS No.: 98946-18-0
- Formula:C6H10Cl3NO
- Molecular Weight:218.51
IUPAC Name: tert-butyl 2,2,2-trichloroacetimidate
InChIKey: CQXDYHPBXDZWBA-UHFFFAOYSA-N
SMILES: N=C(OC(C)(C)C)C(Cl)(Cl)Cl
Biological Activity: tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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tert-Butyl 2,2,2-trichloroacetimidate | 98.15% | tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents. | ||||||||||||||||||||
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References
- [1]. Fandrick KR, et al. A Noncoordinating Acid-Base Catalyst for the Mild and Nonreversible tert-Butylation of Alcohols and Phenols. J Org Chem. 2021 Mar 19;86(6):4877-4882. [Content Brief]
- [2]. Evans LE, et al. Exploitation of Antibiotic Resistance as a Novel Drug Target: Development of a β-Lactamase-Activated Antibacterial Prodrug. J Med Chem. 2019 May 9;62(9):4411-4425. [Content Brief]
