99027-06-2
Chemical Structure
C3 Peptide P16
- CAS No.: 99027-06-2
- Formula:C86H131N25O27
- Molecular Weight:1947.12
IUPAC Name: L-cysteinyl-L-histidyl-L-serylglycyl-L-tyrosyl-L-valylglycyl-L-valyl-L-arginyl-L-cysteine
SMILES: O=C(N1[C@@H](CCC1)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CC(N)=O)NC([C@@H](N)CCCCN)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O
Biological Activity: C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells[1][2].
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C3 Peptide P16 | C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells. | |||||||||||||||||||||
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References
- [1]. Sachdeva R, et al. DING proteins from phylogenetically different species share high degrees of sequence and structure homology and block transcription of HIV-1 LTR promoter. PLoS One. 2013 Aug 6;8(8):e69623. [Content Brief]
- [2]. Frade R, et al. A 16 amino acid synthetic peptide derived from human C3d triggers proliferation and specific tyrosine phosphorylation of transformed CR2-positive human lymphocytes and of normal resting B lymphocytes. Biochem Biophys Res Commun. 1992 Oct 30;188(2):833-42. [Content Brief]
