Cdc7-IN-22
For research use only. We do not sell to patients.
- CAS No.: 1057097-72-9
- Formula: C13H14FN5O
- Molecular Weight:275.28
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
0.5 μM
Compound: S-89
|
Antiproliferative activity against human A2780 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human A2780 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| COLO 205 | IC50 |
0.5 μM
Compound: S-89
|
Antiproliferative activity against human COLO205 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human COLO205 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| HT-29 | IC50 |
4.1 μM
Compound: S-89
|
Antiproliferative activity against human HT-29 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human HT-29 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| L-363 | IC50 |
1.3 μM
Compound: S-89
|
Antiproliferative activity against human L363 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human L363 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| MCF7 | IC50 |
1.1 μM
Compound: S-89
|
Antiproliferative activity against human MCF7 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human MCF7 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| NCI-H929 | IC50 |
1.2 μM
Compound: S-89
|
Antiproliferative activity against human NCI-H929 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human NCI-H929 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| NHDF | IC50 |
1.6 μM
Compound: S-89
|
Antiproliferative activity against human NHDF cells after 72 hrs by luciferase based assay
Antiproliferative activity against human NHDF cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| NIH3T3 | IC50 |
2.5 μM
Compound: S-89
|
Antiproliferative activity against mouse NIH/3T3 cells after 72 hrs by luciferase based assay
Antiproliferative activity against mouse NIH/3T3 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| OPM-2 | IC50 |
3.7 μM
Compound: S-89
|
Antiproliferative activity against human OPM2 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human OPM2 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
| SW48 | IC50 |
0.9 μM
Compound: S-89
|
Antiproliferative activity against human SW48 cells after 72 hrs by luciferase based assay
Antiproliferative activity against human SW48 cells after 72 hrs by luciferase based assay
|
[PMID: 19115845] |
Chemical Information
-
CAS No. 1057097-72-9
-
Molecular Weight 275.28
-
Formula C13H14FN5O
-
SMILES
O=C1C2=C(NC(C3=NC(N)=NC=C3)=C2)[C@@H](CCF)CN1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)