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Cat. No.: HY-112108D

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Chitosan oligosaccharide (MW 2000)

Name: Chitosan oligosaccharide (MW 2000)
Brand: MedChemExpress
SKU: HY-112108D
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: COS (MW 2000))

Customer Review

Based on 1 Customer Validation

Chitosan oligosaccharide (MW 2000) is a natural oligomer derived from chitosan, with a molecular weight of 2000 Da. Chitosan oligosaccharide (MW 2000∼3000 Da) activates the P53, MAPK and NF-κB signaling pathways. As an ideal immunopotentiator, chitosan oligosaccharide is mainly used as a feed additive in aquaculture.

For research use only. We do not sell to patients.

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Chitosan oligosaccharide (MW 2000) Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All NF-κB Isoforms :

In Vitro

Innate ImmunityApoptosis

Innate Immunity

Apoptosis

Chitosan oligosaccharide (MW 2000∼3000 Da) activates the MAPK, NF-κB and p53 signaling pathways in head kidney macrophages of blunt snout bream in a time-dependent manner within 4-16 h^[1].

Apoptosis

Chitosan oligosaccharide (MW 2000∼3000 Da) at a concentration of 20 µg/mL for 16 h significantly induces apoptosis in head kidney macrophages of blunt snout bream^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence^[1]

Cell Line:

blunt snout bream (Megalobrama amblycephala) head kidney macrophages
Concentration:

20 µg/mL
Incubation Time:

16 h
Result:

Exhibited the highest level of apoptosis (both early apoptosis labeled by Annexin V-FITC and late apoptosis labeled by PI) compared to lower molecular weight COS groups and the control group.

Related Protocols :

Research Protocol for Inflammation-related Diseases

Chemical Information

Appearance Solid
Color Light yellow to yellow
SMILES

[Chitosan oligosaccharide (MW 2000)]
Synonyms

COS (MW 2000)
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (Need ultrasonic)

DMSO : 40 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu C, et al. Immunomodulatory Effects and Induction of Apoptosis by Different Molecular Weight Chitosan Oligosaccharides in Head Kidney Macrophages From Blunt Snout Bream (Megalobrama amblycephala). Front Immunol. 2019 May 15;10:869.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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