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Cat. No.: HY-N8404

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Chlorahololide C

Name: Chlorahololide C
Brand: MedChemExpress
SKU: HY-N8404
Price: 480.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC₅₀ of 3.6 μM.

For research use only. We do not sell to patients.

Purity : 98.0%
CAS No.: 1007859-25-7
Formula: C₃₃H₃₆O₉
Molecular Weight:576.63

Storage:

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Chlorahololide C Chemical Structure

CAS No.: 1007859-25-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC₅₀ of 3.6 μM^[1].

IC₅₀ & Target

IC50: 3.6 μM (potassium channel)^[1]

In Vitro

Chlorahololide C (0.1-100 μM) inhibits the delayed rectifier K⁺ current (IK) in rat dissociated hippocampal neurons, with an IC₅₀ of 3.6 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1007859-25-7
Appearance Solid
Molecular Weight 576.63
Formula C₃₃H₃₆O₉
Color White to off-white
SMILES

COC(/C(C)=C1C2=C([C@]([C@@]3([H])[C@]4([H])C3)([C@H](C/1=O)O)C)[C@]4(O)C[C@]([C@@]5([C@@](C([C@]6([H])[C@@]5([H])C6)=C)([H])[C@H]7OC(C)=O)C)([H])[C@@]28C7=C(C(O8)=O)C)=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (280 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang SP, et, al. Chlorahololides C-F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius. Tetrahedron. 2008 Feb; 64(9):2027-2034.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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