Chlorantraniliprole-d3
Chlorantraniliprole-d3 is the deuterated-labeled Chlorantraniliprole (HY-112820). Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ～300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
For research use only. We do not sell to patients.
- CAS No.: 1392493-28-5
- Formula: C18H11D3BrCl2N5O2
- Molecular Weight:486.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
EC50: 40 nM (Drosophila melanogaster Ryanodine receptor), 50 nM (H. virescens Ryanodine receptor), 14 μM (Ryanodine receptor, in C2C12 cells)
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1392493-28-5
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Unlabeled CAS 500008-45-7
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Molecular Weight 486.16
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Formula C18H11D3BrCl2N5O2
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SMILES
O=C(C1=C(C(C)=CC(Cl)=C1)NC(C2=CC(Br)=NN2C3=NC=CC=C3Cl)=O)NC([2H])([2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlorantraniliprole-d3 Related Classifications
HY-W725639 Related Classifications
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