CID-1067700 (Standard)
CID-1067700 (Standard) is the analytical standard of CID-1067700 (HY-13452). This product is intended for research and analytical applications. CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM.
For research use only. We do not sell to patients.
- CAS No.: 314042-01-8
- Formula: C18H18N2O4S2
- Molecular Weight:390.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 314042-01-8
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Molecular Weight 390.48
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Formula C18H18N2O4S2
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SMILES
O=C(C1=C(NC(NC(C2=CC=CC=C2)=O)=S)SC3=C1CC(C)(C)OC3)O
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Synonyms
ML282 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Agola JO, et al. A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition. ACS Chem Biol. 2012 Jun 15;7(6):1095-108. [Content Brief]
[2]. Lam T, et al. Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus. J Immunol. 2016 Nov 15;197(10):3792-3805. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)