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Cat. No.: HY-N22076

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Circumdatin F

Circumdatin F is a benzodiazepine alkaloid found in Aspergillus fungi (such as Aspergillus ochraceus and A. westerdijkiae DFFSCS013). Circumdatin F has antifouling activity, inhibiting the attachment of bryozoan (Bugula neritina) larvae and exhibiting low toxicity to its larvae. Circumdatin F can be used in research related to marine biofouling.

For research use only. We do not sell to patients.

CAS No.: 232922-23-5
Formula: C₁₇H₁₃N₃O₂
Molecular Weight:291.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Circumdatin F Chemical Structure

CAS No.: 232922-23-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

Circumdatin F (1.65-50 μg/mL; 1 h) inhibits settlement of Bugula neritina larvae with an EC₅₀ of 8.81 μg/mL and low toxicity (LC₅₀ >200 μg/mL)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 232922-23-5
Molecular Weight 291.30
Formula C₁₇H₁₃N₃O₂
SMILES

O=C1N2C3=CC=CC=C3C(N[C@H](C2=NC4=CC=CC=C41)C)=O
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Microorganisms
Aspergillus ochraceus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Dai J, et al. Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus. Journal of natural products. 2001 Jan;64(1):125-6.

[2]. Zhang XY, et al. Antifouling potentials of eight deep-sea-derived fungi from the South China Sea. Journal of industrial microbiology & biotechnology. 2014 Apr;41(4):741-8.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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