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Cat. No.: HY-N19184

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Cladobotric acid H

Cladobotric acid H is a polyketide antifungal agent found in the mycoparasitic fungus Hypomyces pseudocorticicola FKA-73. Cladobotric acid H inhibits growth of azole-sensitive and azole-resistant Candida auris, Aspergillus fumigatus, Aspergillus udagawae, Aspergillus felis, and Aspergillus lentulus. Cladobotric acid H can be used for the research of aspergillosis, candidiasis.

For research use only. We do not sell to patients.

CAS No.: 2900278-39-7
Formula: C₂₇H₃₆O₅
Molecular Weight:440.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cladobotric acid H Chemical Structure

CAS No.: 2900278-39-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Fungal Infection

Cladobotric acid H (compound 123) (16-64 μg/mL) inhibits the growth of A. fumigatus IFM 61493, A. fumigatus IFM 62104, and C. auris IFM 65061 with an MIC of 32 μg/mL, A. udagawae IFM 62100, A. felis IFM 62093, and A. lentulus IFM 62073 with an MIC of 64 μg/mL, and C. auris IFM 64524 and C. auris IFM 65059 with an MIC of 16 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2900278-39-7
Molecular Weight 440.58
Formula C₂₇H₃₆O₅
SMILES

C[C@]1([C@@]([C@@H](CC)C)(O1)[H])[C@]2([C@@H](/C=C/C=C/C=C/C(O)=O)[C@]3([C@](C=C2C)(CC(C(OC)=O)=CC3)[H])[H])[H]
Structure Classification
- Others
Initial Source
- Microorganism
Cladobotryum sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang L, et al. Natural Polyketides Act as Promising Antifungal Agents. Biomolecules. 2023 Oct 24;13(11):1572. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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