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Cat. No.: HY-184775

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Clarithromycin 9-oxime

Clarithromycin 9-oxime (Compound 41) is a chemical intermediate of Clarithromycin (HY-17508), a macrolide antibiotic.

For research use only. We do not sell to patients.

CAS No.: 103450-87-9
Formula: C₃₈H₇₀N₂O₁₃
Molecular Weight:762.97

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Clarithromycin 9-oxime Chemical Structure

CAS No.: 103450-87-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Clarithromycin 9-oxime (Compound 41) is a chemical intermediate of Clarithromycin (HY-17508), a macrolide antibiotic^[1].

In Vitro

Clarithromycin 9-oxime (3-20 μM; 3 h accumulation, 3 h washout retention) exhibits cellular accumulation and retention in NCI-H292 cells that follow the established patterns for macrolides, with accumulation driven by lipophilicity (ChromlogD) and retention driven by positive charge (POS)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 103450-87-9
Molecular Weight 762.97
Formula C₃₈H₇₀N₂O₁₃
SMILES

CO[C@](C)(C[C@H](/C([C@@H]([C@H]([C@](O)([C@H](OC([C@@H]([C@H]([C@@H]1C)O[C@H]2C[C@](C)([C@H]([C@@H](O2)C)O)OC)C)=O)CC)C)O)C)=N/O)C)[C@@H]1O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Stepanić V, et al. Modeling cellular pharmacokinetics of 14- and 15-membered macrolides with physicochemical properties. Journal of medicinal chemistry. 2011 Feb 10;54(3):719-33. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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