CYP51/SE-IN-1
CYP51/SE-IN-1 is a dual-target inhibitor of CYP51 and squalene epoxidase (SE), with IC50 values of 2.95 mg/L and 6.35 mg/L, respectively. CYP51/SE-IN-1 is also an Antifungal agent. CYP51/SE-IN-1 disrupts fungal cell membrane integrity, increases membrane permeability, and induces intracellular ROS accumulation. CYP51/SE-IN-1 inhibits ergosterol biosynthesis and exhibits broad-spectrum antifungal activity against plant pathogenic fungi.
For research use only. We do not sell to patients.
- Formula: C21H21F5N4O
- Molecular Weight:440.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CYP51 2.95 μg/mL (IC50) |
In Vitro
CYP51/SE-IN-1 (5-10 mg/L; 30-210 min) increases the cell membrane permeability of V. mali mycelia in a time- and concentration-dependent manner[1].
CYP51/SE-IN-1 (5-10 mg/L) inhibits ergosterol biosynthesis in V. mali, reaching an inhibition rate of 59.94% at 10 mg/L[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 440.41
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Formula C21H21F5N4O
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SMILES
OC(CN1N=CN=C1)(C2=CC=C(F)C=C2F)CN(CC)CC3=CC=C(C(F)(F)F)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CYP51/SE-IN-1 Related Classifications
HY-189445 Related Classifications
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