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Cat. No.: HY-P992533

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DB-1419 antibody

Name: DB-1419 antibody
Brand: MedChemExpress
SKU: HY-P992533
Availability: PreOrder

(Synonyms: DB-141902)

DB-1419 antibody (DB-141902) is a humanized anti-B7-H3/PD-L1 IgG1 bispecific antibody with EC₅₀ values of 0.17 and 2.64 μg/mL for hB7-H3 and hPD-L1, respectively. DB-1419 antibody can be used as an ADC antibody to synthesize ADCs, such as DB-1419. DB-1419 exhibits strong antitumor activity against multiple tumors.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DB-1419 antibody Chemical Structure

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Biological Activity
- Description
- Species Reactivity
- In Vitro
- Target
- Conjugated
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Species Reactivity

Human

In Vitro

DB-1419 antibody binds to hB7-H3 and hPD-L1 (EC₅₀ of 0.17 and 2.64 μg/mL, respectively)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Subcutaneous Cell-Line-Derived Xenograft

Target

B7-H3 & PD-L1

Conjugated

Unconjugated

Application

ELISA, FACS, Functional assay

Chemical Information

SMILES

[DB-1419 antibody]
Synonyms

DB-141902
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Inhibitory Antibodies User Guide (603 KB)

References

[1]. Li C, et al. Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti-B7-H3 × PD-L1 Antibody-Drug Conjugate. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025 Aug 14;31(16):3581-3593.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- Species Reactivity
- In Vitro
- Target
- Conjugated
- Application
Chemical Information
Purity & Documentation
References

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DB-1419 antibody