country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187373

Copy Link Print Information

DDAH1-IN-3

DDAH1-IN-3 is a DDAH1 inhibitor with a human IC₅₀ of 176 μM. DDAH1-IN-3 binds to the DDAH1 active site, forms binding interactions that remodel the binding pocket, and functionally inhibits the enzyme. DDAH1-IN-3 suppresses vasculogenic mimicry in triple-negative breast cancer cells. DDAH1-IN-3 can be used for the research of triple-negative breast cancer.

For research use only. We do not sell to patients.

CAS No.: 1808751-57-6
Formula: C₁₃H₁₉N₃O
Molecular Weight:233.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DDAH1-IN-3 Chemical Structure

CAS No.: 1808751-57-6

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Anti-cancerLocal Vascular Regulation

Anti-cancer

Local Vascular Regulation

DDAH1-IN-3 (Compound A8) (100 μM; 48 h) significantly inhibits vasculogenic mimicry (tube formation and branching formation) in MDA-MB-231 triple-negative breast cancer cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Breast Cancer Modeling

Chemical Information

CAS No. 1808751-57-6
Molecular Weight 233.31
Formula C₁₃H₁₉N₃O
SMILES

CC1=CC(C/N=C(N)/NC2CC2)=CC=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Doman, A. J., et al. (2026). Structure-and Ligand-Based Discovery of Novel Non-Arginine-Based DDAH1 Inhibitors with Anti-Triple-Negative Breast Cancer Activity. ACS Medicinal Chemistry Letters.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote