Desmethyl Erlotinib (Standard)
Desmethyl Erlotinib (Standard) (OSI-420 (free base) (Standard)) is the analytical standard of Desmethyl Erlotinib (HY-13256A). This product is intended for research and analytical applications. Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor. Desmethyl Erlotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 183321-86-0
- Formula: C21H21N3O4
- Molecular Weight:379.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-13256A
Desmethyl ErlotinibErlotinib Active Metabolite -
HY-10325
CL-387785EGFR Inhibitor -
HY-17499
EGFR-IN-12Apoptosis Inducer -
HY-12624
NarazaciclibCDK4/ARK5 Inhibitor -
HY-10251
BMS-599626HER1/2 Inhibitor -
HY-107494R
13-cis-4-Oxoretinoic acid (Standard)Analytical Standard -
HY-129510
4-Methyl erlotinib -
HY-107494
13-cis-4-Oxoretinoic acidMetabolite of Vitamin A -
HY-10325R
CL-387785 (Standard)Standard of CL-387785 -
HY-17499R
EGFR-IN-12 (Standard)Apoptosis Inducer -
HY-103437
EGFR-IN-80EGFR Inhibitor -
HY-129510R
4-Methyl erlotinib (Standard)
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 183321-86-0
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Molecular Weight 379.41
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Formula C21H21N3O4
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SMILES
OCCOC1=CC2=C(N=CN=C2NC3=CC=CC(C#C)=C3)C=C1OCCOC
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Synonyms
OSI-420 free base (Standard); CP-373420 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Thappali SR, et al. Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation.Sci Pharm. 2012 Jul-Sep;80(3):633-46. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Desmethyl Erlotinib (Standard) Related Classifications
HY-13256AR Related Classifications
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