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Cat. No.: HY-145790

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Difluorocyclooctyne-CH2-COOH

Difluorocyclooctyne-CH2-COOH is a difluorinated cyclooctyne (DIFO) analog that can be used for imaging glycans on live cells. Difluorocyclooctyne-CH2-COOH reacts rapidly with azides in live cells without copper catalysis.

For research use only. We do not sell to patients.

CAS No.: 1047997-31-8
Formula: C₁₀H₁₂F₂O₂
Molecular Weight:202.20

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Difluorocyclooctyne-CH2-COOH Chemical Structure

CAS No.: 1047997-31-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Difluorocyclooctyne-CH2-COOH reacts rapidly with azides in live cells without copper catalysis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1047997-31-8
Molecular Weight 202.20
Formula C₁₀H₁₂F₂O₂
SMILES

O=C(O)CC1C(F)(F)C#CCCCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Codelli JA, et al. Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc. 2008;130(34):11486-11493. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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