Dipropyl phthalate-d4
Based on 1 Customer Validation
Dipropyl phthalate-d4 (NSC 15314-d4) is the deuterated-labeled Dipropyl phthalate (HY-B1944). Dipropyl phthalate is an immunomodulator. Dipropyl phthalate alters the activities of acid phosphatase, phenoloxidase and superoxide dismutase, increases the activity of β-glucuronidase in a dose-dependent manner, and elevates the mRNA level of hemocyanin in shrimp. Dipropyl phthalate activates the FoxO signaling pathway, interferes with cell proliferation and apoptosis, downregulates chondrocyte-related genes, and induces craniofacial cartilage developmental malformations in zebrafish embryos. Dipropyl phthalate can be used in studies related to Aeromonas veronii infection and micrognathia syndrome.
For research use only. We do not sell to patients.
- Purity : 99.02%
- CAS No.: 358731-29-0
- Formula: C14H14D4O4
- Molecular Weight:254.31
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- RNA extraction experimental
- Research Protocol for Infectious Diseases
- Annexin V plus membrane-impermeant dye apoptosis staining
- BrdU Incorporation Assay
- Somatic Cell Culture
- CFSE Dye Dilution Proliferation Assay
- Dye-dilution cell tracking and proliferation staining
- CCK-8/WST-8 Cell Proliferation Assay
- Protocol for Cell Cycle
- Cell Counting-Based Growth Curve Assay
- Colony Formation (Clonogenic) Assay
- Real Time qPCR (Q-PCR)
- Cell Viability Determination by MTT Colorimetric Assay
- EdU Incorporation Assay (Click Chemistry-Based DNA Synthesis Measurement)
- Ki-67 Immunostaining Proliferation Assay
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- PCNA Immunodetection Proliferation Assay
- Protocol for Cell Counting and Cell Density Analysis
- Apoptosis Solutions
- MTT Cell Proliferation Assay
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 358731-29-0
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Unlabeled CAS 131-16-8
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Appearance Liquid (Density: 1.082±0.06 g/cm3)
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Molecular Weight 254.31
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Formula C14H14D4O4
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Color Colorless to light yellow
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SMILES
CCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(OCCC)=O)=O
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Synonyms
NSC 15314-d4; Di-n-Propyl phthalate-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (281 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Sung HH, et al. Differential immune responses of the green neon shrimp (Neocaridina denticulate) to dipropyl phthalate. Fish & shellfish immunology. 2011 Sep;31(3):511-5. [Content Brief]
[2]. Shen Q, et al. Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos. Ecotoxicology and environmental safety. 2025 Jan 15;290:117603. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dipropyl phthalate-d4 Related Classifications
HY-B1944S Related Classifications
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Keywords
- Dipropyl phthalate-d4
- 358731-29-0
- NSC 15314-d4
- Di-n-Propyl phthalate-d4
- Isotope-Labeled Compounds
- Apoptosis
- FOXO
- Phosphatase
- β-glucuronidase
- micrognathia syndrome
- chondrocyte-related genes
- Aeromonas veronii
- oxidative stress
- FoxO signaling pathway
- shrimp
- inflammatory response
- zebrafish Foxo1a protein
- Neocaridina denticulate
- zebrafish embryos
- Inhibitor
- inhibitor
- inhibit