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Cat. No.: HY-400610

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DOTA-GA2(tBu)4

Name: DOTA-GA2(tBu)4
Brand: MedChemExpress
SKU: HY-400610
Price: 85.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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DOTA-GA2 (tBu) 4 is a protected DOTA-based chelator precursor that can bind to radionuclides. DOTA-GA2 (tBu) 4 can be used to prepare radionuclide drugs, such as DOTADG-containing Exendin-4 (HY-13443) derivatives.

For research use only. We do not sell to patients.

CAS No.: 1049020-11-2
Formula: C₃₈H₆₈N₄O₁₂
Molecular Weight:772.97

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

DOTA-GA2(tBu)4 Chemical Structure

CAS No.: 1049020-11-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1049020-11-2
Appearance Solid
Molecular Weight 772.97
Formula C₃₈H₆₈N₄O₁₂
SMILES

O=C(CCC(N1CCN(CCN(C(CCC(O)=O)C(OC(C)(C)C)=O)CCN(CC1)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)C(OC(C)(C)C)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Iikuni S, et al. Development of an In-Labeled Glucagon-Like Peptide-1 Receptor-Targeting Exendin-4 Derivative that Exhibits Reduced Renal Uptake. Molecular pharmaceutics. 2022 Mar 07;19(3):1019-1027.

[2]. Hasegawa T, et al. Development of Novel Radiotheranostic Ligand with Positively Charged Unit Targeting Prostate-Specific Membrane Antigen. Journal of medicinal chemistry. 2025 May 22;68(10):10190-10202. [Content Brief]

[3]. Nakashima K, et al. Systematic Investigation of Fatty Acids with Different Carbon-Chain Length as Albumin Binder to Improve Tumor Accumulation of Radioligands. Bioconjugate chemistry. 2026 Jul 15;37(7):1377-1385.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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