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Cat. No.: HY-189541

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DSPE-PEG2000-LTHVVWL

DSPE-PEG2000-LTHVVWL is a PEG compound composed of DSPE and the KIM-1 -targeting peptide (LTHVVWL). LTHVVWL is a KIM-1-targeting peptide that can bind to KIM-1 highly expressed in injured renal tubules. DSPE-PEG2000-LTHVVWL can be used in research related to targeted delivery for renal fibrosis and acute kidney injury.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DSPE-PEG2000-LTHVVWL Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

In Vitro

DSPE-PEG2000-LTHVVWL-modified L/STP/Lipo formed stable liposomes of approximately 108.6 nm, with high STP loading and pH/fibrotic microenvironment-responsive release^[1].
DSPE-PEG2000-LTHVVWL-modified L/STP/Lipo exhibited good biocompatibility with HK-2 cells and caused no significant hemolysis in mouse erythrocytes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

SMILES

[DSPE-PEG2000-LTHVVWL]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhao P, et al. Inhibiting lactylation for efficient treatment of renal fibrosis through targeting nanomedicine of renal lactate accumulation in obstructed kidney. Journal of nanobiotechnology. 2026 Apr 17;24(1):572.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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