Enolicam sodium
Enolicam sodium is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), with a COX IC50 of 1.5 μM and a 5-LOX IC50 of 3.5 μM. Enolicam sodium inhibits arachidonic acid metabolism via the COX and 5-LOX pathways. Enolicam sodium inhibits the production of reactive oxygen species (ROS), superoxide anions, hydrogen peroxide, and the release of polymorphonuclear leukocytes. Enolicam sodium is applicable to research related to acute oxidative lung injury and ocular inflammation.
For research use only. We do not sell to patients.
- CAS No.: 59756-39-7
- Formula: C17H11Cl3NNaO4S
- Molecular Weight:454.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
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COX 1.5 μM (IC50) |
5-LOX 3.5 μM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 59756-39-7
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Molecular Weight 454.69
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Formula C17H11Cl3NNaO4S
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SMILES
O=C(C1=C(C2=C(S(=O)(CC1)=O)C=CC(Cl)=C2)O[Na])NC3=CC=C(C(Cl)=C3)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)