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Cat. No.: HY-W723158A

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Epibestatin

Epibestatin is a molecular glue stabilizer of the 14-3-3/PMA2 complex with a K_d of 1.8 μM. Epibestatin opens stomata and activates plant proton pumps. Epibestatin has potential for cancer research.

For research use only. We do not sell to patients.

CAS No.: 61046-23-9
Formula: C₁₆H₂₄N₂O₄
Molecular Weight:308.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Epibestatin Chemical Structure

CAS No.: 61046-23-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

All 14-3-3 Protein Isoforms :

In Vitro

Epibestatin (50 µM; 3 h) opens stomatal pores in isolated Commelina communis epidermis, with 3.2 µm average opening^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 61046-23-9
Molecular Weight 308.37
Formula C₁₆H₂₄N₂O₄
SMILES

CC(C[C@H](NC([C@H](O)[C@H](N)CC1=CC=CC=C1)=O)C(O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Rose R, et al. Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions. Angew Chem Int Ed Engl. 2010 Jun 1;49(24):4129-32. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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