country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187845

Copy Link Print Information

Estradiol disulfate

Estradiol disulfate is an estradiol disulfate ester, belonging to sulfated steroid derivatives. Estradiol disulfate is a kynurenine transaminase inhibitor that acts by competing with pyridoxal phosphate for the binding site on the apoenzyme. Estradiol disulfate protects kynurenine apo-transaminase from inactivation associated with incubation. Estradiol disulfate can be used for research on kynurenine transaminase-related diseases.

For research use only. We do not sell to patients.

CAS No.: 3233-70-3
Formula: C₁₈H₂₄O₈S₂
Molecular Weight:432.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Estradiol disulfate Chemical Structure

CAS No.: 3233-70-3

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Aminotransferases (Transaminases) Isoforms :

In Vitro

Estradiol disulfate (30 min) effectively inhibits rat kidney kynurenine aminotransferase at concentrations as low as 5 × 10^-7 M^[1].
Estradiol disulfate (5 × 10^-6 M; 1 hour pre-incubation, 24 hours dialysis) reversibly inhibits rat kidney kynurenine aminotransferase and protects the enzyme from inactivation during 1 hour of incubation at 37°^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3233-70-3
Molecular Weight 432.50
Formula C₁₈H₂₄O₈S₂
SMILES

C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OS(=O)(=O)O)=CC4)(CC1)[H])[H])(CC[C@@H]2OS(=O)(=O)O)[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mason M, Gullekson E H. Estrogen-Enzyme Interactions: Inhibition and Protection of Kynurenine Transaminase by the Sulfate Esters of Diethylstilbestrol, Estradiol, and Estrone. Journal of Biological Chemistry, 1960, 235: 1312-1316.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote