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Cat. No.: HY-N12507

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Eupenicisirenin C

Eupenicisirenin C (compound 1) is a sirenin derivative. Eupenicisirenin C has strong NF-κB inhibitory activities. Eupenicisirenin C suppresses effects on cGAS-STING pathway. Eupenicisirenin C inhibits RANKL-induced osteoclast differentiation in bone marrow macrophage cells.

For research use only. We do not sell to patients.

CAS No.: 2968309-12-6
Formula: C₁₃H₁₈O₄
Molecular Weight:238.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Eupenicisirenin C Chemical Structure

CAS No.: 2968309-12-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All NF-κB Isoforms :

Chemical Information

CAS No. 2968309-12-6
Molecular Weight 238.28
Formula C₁₃H₁₈O₄
SMILES

COC(CC[C@]1(C)[C@]2([H])[C@@]1([H])C=C(CC2)C(O)=O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Marine natural products
- Marine microorganism
- Microorganisms
mangrove sediment-derived fungus Penicillium sp. SCSIO 41410.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jian Cai, et al. Discovery of a novel anti-osteoporotic agent from marine fungus-derived structurally diverse sirenins. Eur J Med Chem. 2023. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Eupenicisirenin C

All NF-κB Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Eupenicisirenin C Related Classifications

HY-N12507 Related Classifications

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