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Cat. No.: HY-N21923

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Euphoscopin H

Euphoscopin H is a diterpenoid compound found in the fresh leaves and roots of Euphorbia helioscopia. Euphoscopin H shows weak inhibitory activity against LPS-induced NO production and no obvious cytotoxicity in the mouse microglial BV-2 cell model.

For research use only. We do not sell to patients.

CAS No.: 126239-88-1
Formula: C₃₁H₄₀O₈
Molecular Weight:540.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Euphoscopin H Chemical Structure

CAS No.: 126239-88-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

All NO Synthase Isoforms :

In Vitro

Euphoscopin H (compound 6) exhibits weak inhibitory activity against LPS-induced NO production in the mouse microglial BV-2 cell model, with an IC₅₀ ＞ 100 μM, and shows no obvious cytotoxicity to BV-2 cells at this effective concentration^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 126239-88-1
Molecular Weight 540.64
Formula C₃₁H₄₀O₈
SMILES

O=C1C(C)(C)/C=C/[C@@H](C)[C@@H](OC(C)=O)[C@](C[C@@H](C)[C@@H]2OC(C3=CC=CC=C3)=O)(O)[C@@]2([H])/C=C(C)/[C@H](OC(C)=O)C1
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yamamura S, et al. Diterpenes from Euphorbia helioscopia. Phytochemistry, 1989, 28(12): 3421‑3436.

[2]. Chen H Q, et al. Diterpenes inhibiting NO production from Euphorbia helioscopia. Fitoterapia, 2014, 95: 133‑138.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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