F2276-0106
F2276-0106 is a biochemical reagent targeting the PCAF bromodomain (PDB 5FDZ). F2276-0106 is predicted to have good cell permeability and oral absorption, with physicochemical properties consistent with Lipinski's rule of five. F2276-0106 can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 922054-57-7
- Formula: C19H20N2O5
- Molecular Weight:356.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
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- References
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Help & FAQs
Biological Activity
Description
In Vitro
F2276-0106 exhibits a highly favorable binding free energy with the PCAF bromodomain, at -84.379 kcal/mol[1].
F2276-0106 is predicted to possess favorable drug-like properties, including high human oral absorption and good cell permeability[1].
F2276-0106 has a small HOMO-LUMO energy gap, indicating that it is a chemically reactive molecule with electron transfer potential[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 922054-57-7
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Molecular Weight 356.38
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Formula C19H20N2O5
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SMILES
O=C1C2=CC(=CC=C2OCCN1C)NC(=O)COC3=CC=C(OC)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
F2276-0106 Related Classifications
HY-153144 Related Classifications
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