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Cat. No.: HY-B1657

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Fosphenytoin

Fosphenytoin is a phosphate ester prodrug of Phenytoin (HY-B0448). Fosphenytoin is used in research related to epileptic seizures.

For research use only. We do not sell to patients.

CAS No.: 93390-81-9
Formula: C₁₆H₁₅N₂O₆P
Molecular Weight:362.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (285 KB)

Fosphenytoin Chemical Structure

CAS No.: 93390-81-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Fosphenytoin is a phosphate ester prodrug of Phenytoin (HY-B0448). Fosphenytoin is used in research related to epileptic seizures^[1].

In Vitro

Fosphenytoin disodium (compound VII) converts to phenytoin in rat whole blood and tissue homogenates at 37°C, with a conversion half-life of approximately 30 min in rat whole blood, <30 s in both rat liver and intestinal homogenates, and 57.5 min in dog liver homogenate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Chemical Information

CAS No. 93390-81-9
Molecular Weight 362.27
Formula C₁₆H₁₅N₂O₆P
SMILES

O=C1N(COP(O)(O)=O)C(C(C2=CC=CC=C2)(C3=CC=CC=C3)N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (285 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Varia SA, et al. Phenytoin prodrugs III: water-soluble prodrugs for oral and/or parenteral use. J Pharm Sci. 1984;73(8):1068-1073.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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