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Cat. No.: HY-N20700

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Geministatin A

Geministatin A is a depsipeptide antibiotic. Geministatin A exhibits activity against Gram-positive bacteria. Geministatin A can be used to study bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 3131756-61-8
Formula: C₃₈H₅₂O₁₂
Molecular Weight:700.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Geministatin A Chemical Structure

CAS No.: 3131756-61-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Geministatin A is a depsipeptide antibiotic. Geministatin A exhibits activity against Gram-positive bacteria. Geministatin A can be used to study bacterial infections^[1].

All Antibiotic Isoforms :

In Vitro

Bacterial InfectionFungal InfectionAnti-cancer

Bacterial Infection

Fungal Infection

Anti-cancer

Geministatin A exhibits strong antibacterial activity against Bacillus subtilis (MIC 1.6 µg mL^-1), moderate antibacterial activity against Staphylococcus aureus and MRSA (both MIC 6.3 µg mL^-1), no antifungal activity against Saccharomyces cerevisiae, low cytotoxicity against mouse myeloma NS-1 cells (IC₅₀ 71 µM), and no significant cytotoxicity against neonatal foreskin fibroblast cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Gram Staining of Tissue Sections

Chemical Information

CAS No. 3131756-61-8
Molecular Weight 700.81
Formula C₃₈H₅₂O₁₂
SMILES

CCCCC/C=C\C/C=C\CCCCCCCC1=C(C(O)=CC(O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO)=C1)C(OC3=CC(C)=C(C(O)=C3)C(O)=O)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganism
Austroacremonium gemini
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Crombie A, et al. Geministatins: new depside antibiotics from the fungus Austroacremonium gemini. The Journal of antibiotics. 2024 Oct;77(10):639-646. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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