Gentisuric acid (Standard)
Gentisuric acid (Standard) is the analytical standard of Gentisuric acid (HY-W338852). This product is intended for research and analytical applications. Gentisuric Acid is a metabolite of Aspirin (HY-14654). Gentisuric Acid activates GPR35. Gentisuric Acid inhibits HIF-1α and HIF-2α. Gentisuric Acid inhibits Mitomycin C (HY-13316)-induced genotoxicity and twin spots (mitotic recombination), reduces spot frequency without reducing survival, and modulates replication or repair of Mitomycin C-damaged DNA. Gentisuric Acid can be used in research on VHL-deficient renal cell carcinoma and Drosophila melanogaster infection.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 25351-24-0
- Formula: C9H9NO5
- Molecular Weight:211.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 25351-24-0
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Molecular Weight 211.17
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Formula C9H9NO5
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SMILES
OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Deng H, et al. Aspirin metabolites are GPR35 agonists. Naunyn-Schmiedeberg's archives of pharmacology. 2012 Jul;385(7):729-37. [Content Brief]
[2]. Niikawa M, et al. Effect of cotreatment of aspirin metabolites on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Drug and chemical toxicology. 2006 Jan 1;29(4):379-96. [Content Brief]
[4]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2007;61(2-3):113-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gentisuric acid (Standard) Related Classifications
HY-W338852R Related Classifications
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Keywords
- Gentisuric acid (Standard)
- 25351-24-0
- Reference Standards
- Drug Metabolite
- GPR35
- HIF/HIF Prolyl-Hydroxylase
- Mitosis
- DNA/RNA Synthesis
- Drosophila melanogaster
- HIF-1α
- HIF-2α
- VHL-defective renal carcinoma
- genotoxicity
- mitomycin C
- mitotic recombination
- renal cell carcinoma
- β-arrestin translocation
- Inhibitor
- inhibitor
- inhibit