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Cat. No.: HY-188096

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GLP-1 receptor agonist 24

GLP-1 receptor agonist 24 is a glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1 receptor agonist 24 activates the GLP-1R signaling pathway and regulates glucose metabolism-related responses, including glucose-stimulated insulin secretion and metabolic homeostasis. GLP-1 receptor agonist 24 can be used in studies of metabolism-related diseases.

For research use only. We do not sell to patients.

CAS No.: 3103096-62-1
Formula: C₄₉H₄₆F₂N₁₀O₅
Molecular Weight:892.95

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GLP-1 receptor agonist 24 Chemical Structure

CAS No.: 3103096-62-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Biological Activity

Description

IC₅₀ & Target

^[1]

GLP-1

10 μM (EC₅₀)

In Vitro

GLP-1 receptor agonist 24 (compound 520) exhibits an EC₅₀ of 10 μM for cAMP accumulation, as measured by the HTRF assay in HEK293 cells stably expressing human GLP-1R^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 3103096-62-1
Molecular Weight 892.95
Formula C₄₉H₄₆F₂N₁₀O₅
SMILES

C[C@H]1[C@@](N2C(C(N3[C@@]4([H])C5=C(N6C(N(C7=CC=C(N(N=C8)C)C8=C7F)C=C6)=O)N(C9=CC(C)=C(C(C)=C9)F)N=C5C[C@]3([H])CC4)=O)=CC%10=CC([C@@H]%11CC%12(OCC%11)CC%12)=CC=C%102)(C%13=NOC(N%13)=O)C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kirkberg, et al. Combination of a Menin Inhibitor with a Pyrazolopyrimidine GLP-1 Receptor Agonist for Treating Diabetes and Obesity. WO 2026/055512 A1. World Intellectual Property Organization (WIPO). Published March 12, 2026.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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