GLP-1R agonist 34
Based on 1 Customer Validation
GLP-1R agonist 34 (Compound 1) is an orally active small molecule glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R agonist 34 promotes insulin secretion, inhibits glucagon release, and delays gastric emptying, thereby effectively lowering blood glucose levels. GLP-1R agonist 34 is promising for research of metabolic diseases, including type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).
For research use only. We do not sell to patients.
- Purity : 99.94%
- CAS No.: 3074089-99-6
- Formula: C50H50F2N10O5
- Molecular Weight:908.99
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Description
Chemical Information
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CAS No. 3074089-99-6
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Appearance Solid
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Molecular Weight 908.99
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Formula C50H50F2N10O5
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Color White to off-white
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SMILES
C[C@@H]1[C@](N2C3=CC=C([C@@H]4CC(C)(OCC4)C)C=C3C=C2C(N5[C@H](C6=C(N7C(N(C8=CC=C(N(C9CC9)N=C%10)C%10=C8F)C=C7)=O)N(C%11=CC(C)=C(C(C)=C%11)F)N=C6CC5)C)=O)(C%12=NOC(N%12)=O)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (110.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1001 mL | 5.5006 mL | 11.0012 mL | 27.5031 mL |
| 5 mM | 0.2200 mL | 1.1001 mL | 2.2002 mL | 5.5006 mL | |
| 10 mM | 0.1100 mL | 0.5501 mL | 1.1001 mL | 2.7503 mL | |
| 15 mM | 0.0733 mL | 0.3667 mL | 0.7334 mL | 1.8335 mL | |
| 20 mM | 0.0550 mL | 0.2750 mL | 0.5501 mL | 1.3752 mL | |
| 25 mM | 0.0440 mL | 0.2200 mL | 0.4400 mL | 1.1001 mL | |
| 30 mM | 0.0367 mL | 0.1834 mL | 0.3667 mL | 0.9168 mL | |
| 40 mM | 0.0275 mL | 0.1375 mL | 0.2750 mL | 0.6876 mL | |
| 50 mM | 0.0220 mL | 0.1100 mL | 0.2200 mL | 0.5501 mL | |
| 60 mM | 0.0183 mL | 0.0917 mL | 0.1834 mL | 0.4584 mL | |
| 80 mM | 0.0138 mL | 0.0688 mL | 0.1375 mL | 0.3438 mL | |
| 100 mM | 0.0110 mL | 0.0550 mL | 0.1100 mL | 0.2750 mL |