Glucocorticoid receptor activator 1
Based on 1 Customer Validation
Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR). Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research.
For research use only. We do not sell to patients.
- Purity : 99.34%
- CAS No.: 14593-25-0
- Formula: C11H15Cl2NO2
- Molecular Weight:264.15
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Chemical Information
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CAS No. 14593-25-0
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Appearance Solid
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Molecular Weight 264.15
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Formula C11H15Cl2NO2
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Color White to off-white
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SMILES
CNCC(C1=CC=C(OC(C)=O)C=C1)Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (378.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7857 mL | 18.9286 mL | 37.8573 mL | 94.6432 mL |
| 5 mM | 0.7571 mL | 3.7857 mL | 7.5715 mL | 18.9286 mL | |
| 10 mM | 0.3786 mL | 1.8929 mL | 3.7857 mL | 9.4643 mL | |
| 15 mM | 0.2524 mL | 1.2619 mL | 2.5238 mL | 6.3095 mL | |
| 20 mM | 0.1893 mL | 0.9464 mL | 1.8929 mL | 4.7322 mL | |
| 25 mM | 0.1514 mL | 0.7571 mL | 1.5143 mL | 3.7857 mL | |
| 30 mM | 0.1262 mL | 0.6310 mL | 1.2619 mL | 3.1548 mL | |
| 40 mM | 0.0946 mL | 0.4732 mL | 0.9464 mL | 2.3661 mL | |
| 50 mM | 0.0757 mL | 0.3786 mL | 0.7571 mL | 1.8929 mL | |
| 60 mM | 0.0631 mL | 0.3155 mL | 0.6310 mL | 1.5774 mL | |
| 80 mM | 0.0473 mL | 0.2366 mL | 0.4732 mL | 1.1830 mL | |
| 100 mM | 0.0379 mL | 0.1893 mL | 0.3786 mL | 0.9464 mL |