GSDMD ligand-1
GSDMD ligand-1 (compound A5) is a synthetic intermediate. GSDMD ligand-1 is used for conjugation with Thalidomide (HY-14658)/CRBN linker fragments to construct PROTACs targeting GSDMD. GSDMD ligand-1 can be used in cancer-related research.
For research use only. We do not sell to patients.
- Formula: C26H23F2N3O4
- Molecular Weight:479.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
GSDMD |
Chemical Information
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Molecular Weight 479.48
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Formula C26H23F2N3O4
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SMILES
OC(C1=CC=C(C=C1)C(NC2=CC=C(C=C2)N3CCN(CC3)C(CC4=C(C=C(C=C4)F)F)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- GSDMD ligand-1
- GSDMD ligand1
- GSDMD ligand 1
- Drug Intermediate
- Synthetic Intermediate
- GSDMD ligand
- GSDMD binder
- GSDMD warhead
- 4-((4-(4-(2-(2
- 4-difluorophenyl)acetyl)piperazin-1-yl)phenyl)carbamoyl)benzoic acid
- PGC analog
- PROTAC building block
- CRBN-recruiting GSDMD PROTAC precursor
- pyroptosis research intermediate
- inflammasome research intermediate
- full-length GSDMD targeting scaffold
- PGC-01 precursor intermediate
- Inhibitor
- inhibitor
- inhibit