GSPT1 degrader-6
GSPT1 degrader-6 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 13 nM. GSPT1 degrader-6 induces GSPT1 protein degradation via the ubiquitin-proteasome pathway. GSPT1 degrader-6 can be used in breast cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 3034764-41-2
- Formula: C24H22ClN5O5
- Molecular Weight:495.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All Eukaryotic Release Factor (eRF) Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
eRF3a/GSPT1 13 nM (DC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3034764-41-2
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Molecular Weight 495.91
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Formula C24H22ClN5O5
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SMILES
ClC1=CC(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)=CC=C1NC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSPT1 degrader-6 Related Classifications
HY-162535 Related Classifications
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