H-APPAMP-010
H-APPAMP-010 is a Cyclin K degrader and CDK12/7 inhibitor with IC50 values of 40 and 238 nM for CDK12/7, respectively. H-APPAMP-010 inhibits cancer cell viability. H-APPAMP-010 can be used for cancer research.
For research use only. We do not sell to patients.
- Formula: C24H32N8O
- Molecular Weight:448.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CDK7 238 nM (IC50) |
CDK12 40 nM (IC50) |
CDK12/Cyclin K |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 448.56
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Formula C24H32N8O
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SMILES
CC1=CC=CC2=NC=C(CNC3=CC(NC[C@H]4CCNC[C@@H]4O)=NC5=C(C(C)C)C=NN35)N12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
H-APPAMP-010 Related Classifications
HY-190278 Related Classifications
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