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Cat. No.: HY-189309

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HDAC-IN-106

HDAC-IN-106 is a competitive HDAC inhibitor with an IC₅₀ of 22.9 nM against Pa-HDAC. HDAC-IN-106 can be used for research on southern corn rust and soybean rust.

For research use only. We do not sell to patients.

Formula: C₂₀H₁₇F₃N₄O₅S
Molecular Weight:482.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC-IN-106 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

HDAC-IN-106 is a competitive HDAC inhibitor with an IC₅₀ of 22.9 nM against Pa-HDAC. HDAC-IN-106 can be used for research on southern corn rust and soybean rust^[1].

All HDAC Isoforms :

In Vitro

HDAC-IN-106 (Compound 9q) (0-35 nM) is a competitive inhibitor of Pa-HDAC with an IC₅₀ of 22.9 nM and a K_i of 24.95 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 482.43
Formula C₂₀H₁₇F₃N₄O₅S
SMILES

O=C(NC/C(C1=CC=C(S(=O)(C)=O)C=C1)=N\OC)C2=CC=C(C3=NOC(C(F)(F)F)=N3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Dong S, et al. Structure-Based Discovery of Trifluoromethyl Oxadiazole Oxime Ethers as Potent Histone Deacetylase Inhibitors. Journal of agricultural and food chemistry. 2026 Sep 02;74(34):27247-27257.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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