HDAC4/HDAC7-IN-1
HDAC4/HDAC7-IN-1 is a TMP269 (HY-18360)-derived HDAC4/HDAC7 selective inhibitor. HDAC4/HDAC7-IN-1 selectively inhibits HDAC7-dependent transcription relative to HDAC4-dependent transcription. HDAC4/HDAC7-IN-1 selectively disrupts the HDAC7-Aiolos protein interaction but does not interfere with the HDAC4-JunB complex.=HDAC4/HDAC7-IN-1 can be used for research on HDAC4/HDAC7-mediated related diseases, such as inflammatory diseases.
For research use only. We do not sell to patients.
- Formula: C27H25F3N4O2S
- Molecular Weight:526.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
HDAC7 |
HDAC4 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 526.57
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Formula C27H25F3N4O2S
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SMILES
O=C(C1=CC(C2=CN(C(F)(F)F)N=C2)=CC(C)=C1)NCC3(CCOCC3)C4=NC(C5=CC=CC=C5)=CS4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)