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Cat. No.: HY-189867

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Herbicidal agent 18

Herbicidal agent 18 is a Herbicide. Herbicidal agent 18 binds AFB5 and enhances the AFB5-IAA interaction (K_d = 0.97 μM). Herbicidal agent 18 induces the transcription of auxin-related genes AUX1, GH3.3, and IAA5 in Arabidopsis. Herbicidal agent 18 induces root shortening, leaf curling, wilting, and plant death.

For research use only. We do not sell to patients.

Formula: C₁₇H₁₂Cl₂N₂O₂
Molecular Weight:347.20

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Please store the product under the recommended conditions in the Certificate of Analysis.

Herbicidal agent 18 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
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Biological Activity

Description

In Vitro

Herbicidal agent 18 (Compound 8o) enhances the AtAFB5-AtIAA7DI-DII interaction with a K_d of 0.97 μM in MST^[1].
Herbicidal agent 18 (0.1 ppm (A. thaliana); 1 ppm (A. theophrasti); 200 ppm (E. crus-galli); 7-14 days) inhibits A. thaliana growth by 94.9% at 0.1 ppm and produces auxin-like root and foliar symptoms^[1].
Herbicidal agent 18 (3.75-7.5 g ai/ha (weed control); 30 g ai/ha (crop safety)) maintains over 80% control of five weed species at 3.75 g ai/ha and is selective for rice, wheat, and corn at 30 g ai/ha^[1].
Herbicidal agent 18 (12-24 h) increases expression of the auxin-related genes AUX1, GH3.3, and IAA5 in A. thaliana seedlings at 12 and 24 h^[1].
Herbicidal agent 18 is nonmutagenic in Salmonella typhimurium TA98, TA100, TA1535 and Escherichia coli WP2 uvrA (pKM101)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 347.20
Formula C₁₇H₁₂Cl₂N₂O₂
SMILES

NC1=C(Cl)C(C(OC)=O)=NC(C2=C3C=CC=CC3=C(Cl)C=C2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yang W Y, et al. Pocket-Oriented Design of Benzene-Fused Pyridinecarboxylates as Potent Synthetic Auxin Herbicides[J]. Journal of Agricultural and Food Chemistry, 2026, 74(38): 29898-29908.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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