hIAPP22–27
hIAPP22-27 is a hexapeptide corresponding to residues 22-27 of human islet amyloid polypeptide (hIAPP) and is the key amyloid core sequence of hIAPP. hIAPP22-27 can self-assemble under neutral pH conditions to form β-sheet-containing amyloid fibrils and is cytotoxic to pancreatic β cells. hIAPP22-27 can be used in research related to type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 121341-41-1
- Formula: C30H47N7O8
- Molecular Weight:633.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 121341-41-1
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Molecular Weight 633.74
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Formula C30H47N7O8
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SMILES
O=C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N
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Sequence
Asn-Phe-Gly-Ala-Ile-Leu
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Sequence Shortening
NFGAIL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hIAPP22–27 Related Classifications
HY-P12374 Related Classifications
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