IKZF2 degrader-6
IKZF2 degrader-6 is an IKZF2 molecular glue degrader. IKZF2 degrader-6 binds to and alters the surface structure of the CRL4CRBN E3 ubiquitin ligase, thereby recruiting and mediating the ubiquitination and proteasomal degradation of IKZF2. IKZF2 degrader-6 can be used for research on acute myeloid leukemia.
For research use only. We do not sell to patients.
- Formula: C24H26N4O3
- Molecular Weight:418.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IZKF2 |
Cereblon-DDB1 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Molm-13 cells
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Concentration:1 μM
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Incubation Time:16 h
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Result:Effectively induced the degradation of IKZF2 protein in Molm-13 cells at a concentration of 1 μM, demonstrating excellent degradation activity with a degradation rate > 70% (Grade A).
Chemical Information
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Molecular Weight 418.49
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Formula C24H26N4O3
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SMILES
O=C(C(N1NC2=C(C=CC(C3CCN(CC4=CC=CC=C4)CC3)=C2)C1=O)CC5)NC5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IKZF2 degrader-6 Related Classifications
HY-190241 Related Classifications
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