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Cat. No.: HY-187834

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Inositol 4-phosphate

Name: Inositol 4-phosphate
Brand: MedChemExpress
SKU: HY-187834
Availability: PreOrder

(Synonyms: IP1)

Inositol 4-phosphate (IP1) is an inositol monophosphate isomer derived from the dephosphorylation of I(1,4)P₂. Inositol 4-phosphate increases rapidly in GH3 cells after thyrotropin-releasing hormone stimulation. Inositol 4-phosphate can be used in glioma-related research.

For research use only. We do not sell to patients.

CAS No.: 46495-39-0
Formula: C₆H₁₃O₉P
Molecular Weight:260.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Inositol 4-phosphate Chemical Structure

CAS No.: 46495-39-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
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Biological Activity

Description

All Endogenous Metabolite Isoforms :

In Vitro

Inositol 4-phosphate (IP₁) accumulates in C6 glioma cells in a time- and concentration-dependent manner upon histamine stimulation (EC₅₀ = 4.1 μM)^[1].
Inositol 4-phosphate (I4P) accumulates in GH₃ cells following TRH stimulation; its levels rise rapidly within 30 s and continue to increase for up to 30 min; moreover, it is separable from other inositol phosphate isomers using anion-exchange HPLC^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Endocrine Diseases

Chemical Information

CAS No. 46495-39-0
Molecular Weight 260.13
Formula C₆H₁₃O₉P
SMILES

O(P(=O)(O)O)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
Synonyms

IP1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tseng CL, et al. Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. Journal of the Chinese Medical Association : JCMA. 2012 Apr;75(4):143-50.

[2]. Shyng SL, et al. Membrane phospholipid control of nucleotide sensitivity of KATP channels. Science. 1998 Nov 6;282(5391):1138-41.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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