Insecticidal agent 42
Insecticidal agent 42 is an insecticide. Insecticidal agent 42 inhibits AChE, leading to acetylcholine accumulation and disruption of neurotransmission. Insecticidal agent 42 binds to the active pocket of AChBP, interfering with neural signaling pathways. Insecticidal agent 42 inhibits Ca2+, Mg2+-ATPase and Na+, K+-ATPase. Insecticidal agent 42 disrupts neuronal homeostasis, causing insect death, and exhibits systemic root-to-stem transport. Insecticidal agent 42 can be used for insecticidal research.
For research use only. We do not sell to patients.
- Formula: C17H17ClN4O4S
- Molecular Weight:408.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE |
In Vivo
Insecticidal agent 42 (10 mg/L; 48 h) exhibits high control efficacy against M. crassicauda in pot experiments, achieving 79.2% mortality at 10 mg/L[1].
Insecticidal agent 42 (12-36 h) exerts its insecticidal effect by inhibiting AChE activity and interfering with neurotransmission in M. crassicauda[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Megoura crassicauda (wingless individuals from a colony established from a field population and maintained in the laboratory for over 50 generations on broad bean (Vicia faba L.) seedlings)[1]
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Dosage:100, 10, and 1 mg/L
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Administration:spray application; mortality assessed at 48 h; root-dip
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Result:Exhibited an LC50 = 1.83 mg/L against M. crassicauda after 48 h of application.
Exhibited an LC50 of 4.63 mg/L in the systemic activity assessment via the root-dip method.
Chemical Information
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Molecular Weight 408.86
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Formula C17H17ClN4O4S
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SMILES
O=C1C(CNC(OC(C)C)=O)=C([O-])[N+](CC2=CN=C(Cl)S2)=C3C=CC=CN31
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Insecticidal agent 42 Related Classifications
HY-189444 Related Classifications
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Keywords
- Insecticidal agent 42
- Insecticidal agent42
- Insecticidal agent-42
- Insecticide
- Cholinesterase (ChE)
- nAChR
- Na+/K+ ATPase
- Proton Pump
- Ca2+
- Mg2+-ATPase
- nicotinic acetylcholine receptor
- Ls-AChBP
- acetylcholine-binding protein
- glutathione S-transferase
- M. crassicauda
- acetylcholinesterase
- Apis mellifera
- Na+
- K+-ATPase
- carboxylesterase
- Inhibitor
- inhibitor
- inhibit