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Cat. No.: HY-188130

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Insecticidal agent 43

Insecticidal agent 43 is an insecticide derived from Celangulin V (HY-N7202) that targets the V-ATPase H subunit of Mythimna separata. Insecticidal agent 43 exhibits stomach toxicity toward the 3rd-instar larvae of Mythimna separata and demonstrates insecticidal activity. Insecticidal agent 43 can be used in research related to pest control.

For research use only. We do not sell to patients.

Formula: C₁₆H₁₇NO₂
Molecular Weight:255.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Insecticidal agent 43 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Insecticidal agent 43 (compound 6.16) and Celangulin V (HY-N7202) bind to the same active pocket on the V-ATPase subunit H of Mythimna separata, and can interact with the unique residue Asn231 as well as the common residues Ser331 and Arg333, indicating that both agents share a common molecular target^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Insecticidal agent 43 (compound 6.16): The stomach poisoning LC₅₀ against Mythimna separata is 0.224 mg/mL, and the contact toxicity LD₅₀ is 0.951 μg/larva; its LC₅₀ against Plutella xylostella is 0.796 mg/mL, and it exhibits moderate insecticidal activity against Rhopalosiphum padi^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 255.31
Formula C₁₆H₁₇NO₂
SMILES

C=CCOC1=C(CCC/C2=N\OCC#C)C2=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Qian H, et al. In-Depth Structural Simplification of Celangulin V: Design, Synthesis, and Biological Activity. Journal of agricultural and food chemistry. 2024 Jul 10;72(27):15142-15150.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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