Calcium mesoxalate
Based on 1 publication(s) in Google Scholar
Calcium mesoxalate (Ketomalonic acid calcium) is an orally active antidiabetic agent. Calcium mesoxalate increases pancreatic insulin content. Calcium mesoxalate reduces dietary hyperglycemia. Calcium mesoxalate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Calcium mesoxalate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Calcium mesoxalate can be used in diabetes-related research.
For research use only. We do not sell to patients.
- CAS No.: 21085-60-9
- Formula: C3CaO5
- Molecular Weight:156.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Calcium mesoxalate
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Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 21085-60-9
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Appearance Solid
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Molecular Weight 156.11
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Formula C3CaO5
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Color White to off-white
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SMILES
O=C(C([O-])=O)C([O-])=O.[Ca+2]
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Synonyms
Ketomalonic acid calcium; Mesoxalic acid calcium; Oxomalonic acid calcium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Bernatchez JA, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of biological chemistry. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. Davis WR, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]
[3]. TAKEUCHI S. Effect of mesoxalate on insulin content of pancreas. Endocrinol Jpn. 1958 Sep;5(3):177-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)