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Cat. No.: HY-19332R

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Kifunensine (Standard)

Name: Kifunensine (Standard)
Brand: MedChemExpress
SKU: HY-19332R
Price: 540.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: FR-900494 (Standard))

Kifunensine (Standard) (FR-900494 (Standard)) is the analytical standard of Kifunensine (HY-19332). This product is intended for research and analytical applications. Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD.

For research use only. We do not sell to patients.

Purity : 98%
CAS No.: 109944-15-2
Formula: C₈H₁₂N₂O₆
Molecular Weight:232.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Kifunensine (Standard) Chemical Structure

CAS No.: 109944-15-2

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 109944-15-2
Molecular Weight 232.19
Formula C₈H₁₂N₂O₆
SMILES

O=C(N1[C@@](N2)([H])[C@@H](O)[C@@H](O)[C@H](O)[C@H]1CO)C2=O
Synonyms

FR-900494 (Standard)
Structure Classification
- Alkaloids
- Piperidine Alkaloids
Initial Source
- Microorganisms
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Yongao Xiong, et al. Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration. Int J Mol Sci. 2018 Mar; 19(3): 890.

[2]. Hiroshi Kayakiri, et al. Structure of Kifunensine, a New Immunomodulator Isolated from an Actinomycete. J. Org. Chem. 1989,54,4015-4016.

[3]. Qun Zhou, et al. Development of a Simple and Rapid Method for Producing Non-Fucosylated Oligomannose Containing Antibodies With Increased Effector Function. Biotechnol Bioeng. 2008 Feb 15;99(3):652-65. [Content Brief]

[4]. Hyung Lim Elfrink, et al. Inhibition of Endoplasmic Reticulum Associated Degradation Reduces Endoplasmic Reticulum Stress and Alters Lysosomal Morphology and Distribution. Mol Cells. 2013 Apr 30; 35(4): 291–297. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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