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Cat. No.: HY-117671

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KS IV

KS IV is a cyclolignan derivative and antigonadotropic agent. KS IV exhibits activity against pregnant mare serum gonadotropin (PMSG) but shows no activity against luteinizing hormone (LH). KS IV abolishes the stimulatory effect of PMSG on testosterone release from isolated mouse Leydig cells. KS IV can be used in studies on gonadotropin-regulated endocrine functions.

For research use only. We do not sell to patients.

CAS No.: 121242-02-2
Formula: C₁₇H₁₂O₆
Molecular Weight:312.27

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

KS IV Chemical Structure

CAS No.: 121242-02-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

In Vitro

KS IV (compound 2) (0.09-0.9 μg) completely inhibits testosterone release from isolated mouse Leydig cells induced by 0.05 IU PMSG (HY-N12634)^[1].
KS IV (0.09-0.9 μg) shows no activity against testosterone release induced by 25 ng LH (HY-P2293) in isolated mouse Leydig cells^[1].
The relative molecular mass of KS IV determined by negative-ion FAB mass spectrometry is 312^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Endocrine Diseases

Chemical Information

CAS No. 121242-02-2
Appearance Solid
Molecular Weight 312.27
Formula C₁₇H₁₂O₆
Color White to off-white
SMILES

OC1=CC=C(C=C1O)C2=C3C=C(C(O)=CC3=CC(C(O)=O)=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (284 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nahrstedt A, et al. Structures of compounds with antigonadotropic activity obtained by in vitro oxidation of caffeic acid. Planta medica. 1990 Aug;56(4):395-8.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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