L-Homocysteine-d4
Based on 2 publication(s) in Google Scholar
L-Homocysteine-d4 is deuterium labeled L-Homocysteine (HY-W010347). L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia
For research use only. We do not sell to patients.
- Purity : 98.78%
- CAS No.: 331665-12-4
- Formula: C4H5D4NO2S
- Molecular Weight:139.21
-
Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Homocysteine-d4
MoreAll Endogenous Metabolite Isoforms
MoreAll Cathepsin Isoforms
More
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 331665-12-4
-
Unlabeled CAS 6027-13-0
-
Appearance Solid
-
Molecular Weight 139.21
-
Formula C4H5D4NO2S
-
Color White to off-white
-
SMILES
SC([2H])([2H])C([2H])([2H])[C@H](N)C(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
-
J Pharm Biomed Anal
A rapid LC-MS/MS method for the simultaneous quantification of 10 key folate cycle intermediates in human plasma. [Abstract]2026 Jan 15:268:117178. PMID: 41061512
Solvent & Solubility
In Vitro:
H2O : 25 mg/mL (179.58 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.1834 mL | 35.9170 mL | 71.8339 mL | 179.5848 mL |
| 5 mM | 1.4367 mL | 7.1834 mL | 14.3668 mL | 35.9170 mL | |
| 10 mM | 0.7183 mL | 3.5917 mL | 7.1834 mL | 17.9585 mL | |
| 15 mM | 0.4789 mL | 2.3945 mL | 4.7889 mL | 11.9723 mL | |
| 20 mM | 0.3592 mL | 1.7958 mL | 3.5917 mL | 8.9792 mL | |
| 25 mM | 0.2873 mL | 1.4367 mL | 2.8734 mL | 7.1834 mL | |
| 30 mM | 0.2394 mL | 1.1972 mL | 2.3945 mL | 5.9862 mL | |
| 40 mM | 0.1796 mL | 0.8979 mL | 1.7958 mL | 4.4896 mL | |
| 50 mM | 0.1437 mL | 0.7183 mL | 1.4367 mL | 3.5917 mL | |
| 60 mM | 0.1197 mL | 0.5986 mL | 1.1972 mL | 2.9931 mL | |
| 80 mM | 0.0898 mL | 0.4490 mL | 0.8979 mL | 2.2448 mL | |
| 100 mM | 0.0718 mL | 0.3592 mL | 0.7183 mL | 1.7958 mL |
L-Homocysteine-d4 Related Classifications
HY-W653733 Related Classifications
Powered by Bioz