L-Lactic acid calcium hydrate
Based on 16 publication(s) in Google Scholar
L-Lactic acid calcium hydrate is the calcium salt of L-Lactic acid. L-Lactic acid calcium hydrate is a building block that can be used as a precursor for the production of bioplastic polymer polylactic acid.
For research use only. We do not sell to patients.
- Assay : 98.8%
- CAS No.: 865717-20-0
- Formula: C3H6O3·1/2Ca·5/2H2O
- Molecular Weight:155.17
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Lactic acid calcium hydrate
More- Autophagy. 2026 Jul 8:1-18. [Abstract]
- Mol Cell. 2026 Sep 3;86(17):3529-3544.e9.
- Adv Sci (Weinh). 2025 Feb;12(8):e2411943. [Abstract]
- Adv Sci (Weinh). 2024 Mar;11(10):e2304761. [Abstract]
- Small. 2022 Apr;18(13):e2107236. [Abstract]
- Phytomedicine. 2026 Sep:159:158525.
- Diabetologia. 2024 Jul;67(7):1429-1443. [Abstract]
- Cell Chem Biol. 2026 Feb 19;33(2):213-226.e5. [Abstract]
- Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098. [Abstract]
- Int J Biol Macromol. 2022 Dec 1;222(Pt B):2225-2243. [Abstract]
- Commun Chem. 2025 Dec 9. [Abstract]
- J Autoimmun. 2025 May:153:103411. [Abstract]
- J Ethnopharmacol. 2025 Jan 31:340:119287. [Abstract]
- Cells. 2026 Jul 9;15(14):1240.
- Int Immunopharmacol. 2024 Jan 5:126:111265. [Abstract]
- PLoS One. 2025 Sep 18;20(9):e0332825. [Abstract]
Customer Validation & Images
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RT-PCR
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Cell Proliferation/Viability Assay
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Cell Migration/Invasion Assay
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Cell Proliferation/Viability Assay
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WB
Biological Activity
Description
Chemical Information
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CAS No. 865717-20-0
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Appearance Powder
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Molecular Weight 155.17
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Formula C3H6O3·1/2Ca·5/2H2O
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SMILES
[O-]C([C@@H](O)C)=O.[Ca+2].O.[1/2].[5/2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (16)
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Journal Impact Factor
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Most Recent
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Autophagy
AARS2-mediated lactylation of ULK1 promotes autophagy-dependent progression of clear cell renal cell carcinoma. [Abstract]2026 Jul 8:1-18. PMID: 42381569 -
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Adv Sci (Weinh)
Aldehyde Dehydrogenase 2 Lactylation Aggravates Mitochondrial Dysfunction by Disrupting PHB2 Mediated Mitophagy in Acute Kidney Injury. [Abstract]2025 Feb;12(8):e2411943. PMID: 39737891 -
Adv Sci (Weinh)
Enzymatically Bioactive Nucleus Pulposus Matrix Hydrogel Microspheres for Exogenous Stem Cells Therapy and Endogenous Repair Strategy to Achieve Disc Regeneration. [Abstract]2024 Mar;11(10):e2304761. PMID: 38145353
L-Lactic acid calcium hydrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Mar;11(10):e2304761. [Abstract]
Evaluation of the viability of BMSCs cultured on microspheres with or without lactate (L-Lactic acid; 6 mM) for 24 h. Fluorescence images of the live/dead assays of BMSCs cultured on microspheres with or without lactate for 24 h.
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Small
Stemness Maintenance and Massproduction of Neural Stem Cells on Poly L-Lactic Acid Nanofibrous Membrane Based on Piezoelectriceffect. [Abstract]2022 Apr;18(13):e2107236. PMID: 35166031 -
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Diabetologia
2024 Jul;67(7):1429-1443. PMID: 38676722 -
Cell Chem Biol
2026 Feb 19;33(2):213-226.e5. PMID: 41643668 -
Int J Biol Macromol
Lactate-related genes signature as a novel prognostic landscape in laryngeal squamous cell carcinoma: insights from 156 machine learning algorithms and in vitro validation. [Abstract]2025 Aug 24;323(Pt 1):147098. PMID: 40858160
L-Lactic acid calcium hydrate purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098. [Abstract]
Lactate (L-Lactic acid; 24 h) TU668 cells, the expression levels of hub genes were quantified by PCR.
L-Lactic acid calcium hydrate purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098. [Abstract]
Lactate (L-Lactic acid; 15 mM; 24, 48, 72 h) cell viability was assessed using the CCK-8 assay in TU686 cells.
L-Lactic acid calcium hydrate purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098. [Abstract]
Lactate (L-Lactic acid; 15 mM; 0, 48 h), cell migration capacity was evaluated via a scratch wound healing assay in TU686 cells.
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Int J Biol Macromol
HIF1α lactylation enhances KIAA1199 transcription to promote angiogenesis and vasculogenic mimicry in prostate cancer. [Abstract]2022 Dec 1;222(Pt B):2225-2243. PMID: 36209908
L-Lactic acid calcium hydrate purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2022 Dec 1;222(Pt B):2225-2243. [Abstract]
Assessed by WB, extracellular lactate (L-Lactic acid) treatment (10 mM, 72 h) significantly increased VE-cadherin and p-EphA2 (Ser897) expressions, which could be reversed by MCT1 silencing PC-3 cells.
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Commun Chem
Stepped collisional energy improves protein acylation identification by eliminating positional bias of cyclic immonium ions. [Abstract]2025 Dec 9. PMID: 41366033 -
J Autoimmun
Neutrophil extracellular traps induce trophoblasts pyroptosis via enhancing NLRP3 lactylation in SLE pregnancies. [Abstract]2025 May:153:103411. PMID: 40179478 -
J Ethnopharmacol
Icariin maintaining TMEM119-positive microglial population improves hippocampus-associated memory in senescent mice in relation to R-3-hydroxybutyric acid metabolism. [Abstract]2025 Jan 31:340:119287. PMID: 39736348 -
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Int Immunopharmacol
Identifying the critical oncogenic mechanism of LDHA based on a prognostic model of T-cell synthetic drivers. [Abstract]2024 Jan 5:126:111265. PMID: 38000233 -
PLoS One
2025 Sep 18;20(9):e0332825. PMID: 40966256
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (644.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4445 mL | 32.2227 mL | 64.4454 mL | 161.1136 mL |
| 5 mM | 1.2889 mL | 6.4445 mL | 12.8891 mL | 32.2227 mL | |
| 10 mM | 0.6445 mL | 3.2223 mL | 6.4445 mL | 16.1114 mL | |
| 15 mM | 0.4296 mL | 2.1482 mL | 4.2964 mL | 10.7409 mL | |
| 20 mM | 0.3222 mL | 1.6111 mL | 3.2223 mL | 8.0557 mL | |
| 25 mM | 0.2578 mL | 1.2889 mL | 2.5778 mL | 6.4445 mL | |
| 30 mM | 0.2148 mL | 1.0741 mL | 2.1482 mL | 5.3705 mL | |
| 40 mM | 0.1611 mL | 0.8056 mL | 1.6111 mL | 4.0278 mL | |
| 50 mM | 0.1289 mL | 0.6445 mL | 1.2889 mL | 3.2223 mL | |
| 60 mM | 0.1074 mL | 0.5370 mL | 1.0741 mL | 2.6852 mL | |
| 80 mM | 0.0806 mL | 0.4028 mL | 0.8056 mL | 2.0139 mL | |
| 100 mM | 0.0644 mL | 0.3222 mL | 0.6445 mL | 1.6111 mL |
L-Lactic acid calcium hydrate Related Classifications
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